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Deletion of extra domain A of fibronectin reduces acute myocardial ischemia/reperfusion injury in hyperlipidemic mice by limiting thrombo-inflammation

BACKGROUND: Fibronectin splicing variant containing extra domain A (Fn-EDA), which is an endogenous ligand for toll-like-receptor 4 (TLR4), is present in negligible amounts in the plasma of healthy humans, but markedly elevated in patients with comorbid conditions including diabetes and hyperlipidem...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Thromb Haemost
Prif Awduron: Chorawala, Mehul R, Prakash, Prem, Doddapattar, Prakash, Jain, Manish, Dhanesha, Nirav, Chauhan, Anil K.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7027995/
https://ncbi.nlm.nih.gov/pubmed/29960272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0038-1661353
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