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Deletion of extra domain A of fibronectin reduces acute myocardial ischemia/reperfusion injury in hyperlipidemic mice by limiting thrombo-inflammation
BACKGROUND: Fibronectin splicing variant containing extra domain A (Fn-EDA), which is an endogenous ligand for toll-like-receptor 4 (TLR4), is present in negligible amounts in the plasma of healthy humans, but markedly elevated in patients with comorbid conditions including diabetes and hyperlipidem...
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| Publicado no: | Thromb Haemost |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7027995/ https://ncbi.nlm.nih.gov/pubmed/29960272 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0038-1661353 |
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