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Fibronectin containing extra domain A induces plaque destabilization in the innominate artery of aged apolipoprotein E-deficient mice

OBJECTIVE: Fibronectin containing extra domain A (Fn-EDA) is an endogenous ligand of toll like-receptor 4 (TLR4) and is abundant in the extracellular matrix (ECM) of advanced atherosclerotic lesions in human and mice. Irrespective of gender, deletion of Fn-EDA reduces early atherosclerosis in apolip...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Doddapattar, Prakash, Jain, Manish, Dhanesha, Nirav, Lentz, Steven R., Chauhan, Anil K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5823768/
https://ncbi.nlm.nih.gov/pubmed/29326316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.117.310345
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