Endothelial cell-derived von Willebrand factor, but not platelet-derived, promotes atherosclerosis in Apoe-deficient mice

OBJECTIVE: von Willebrand factor (VWF) is synthesized by endothelial cells and megakaryocytes, and is known to contribute to atherosclerosis. In vitro studies suggest that platelet-derived VWF (Plt-VWF) is biochemically and functionally different from endothelial cell-derived VWF (EC-VWF). We determ...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Arterioscler Thromb Vasc Biol
Huvudupphovsmän: Doddapattar, Prakash, Dhanesha, Nirav, Chorawala, Mehul R., Tinsman, Chandler, Jain, Manish, Nayak, Manasa K., Staber, Janice M., Chauhan, Anil K.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2018
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5823769/
https://ncbi.nlm.nih.gov/pubmed/29348121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.117.309918
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk