Content and activity of human liver microsomal protein and prediction of individual hepatic clearance in vivo

The lack of information concerning individual variation in content and activity of human liver microsomal protein is one of the most important obstacles for designing personalized medicines. We demonstrated that the mean value of microsomal protein per gram of liver (MPPGL) was 39.46 mg/g in 128 hum...

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Pubblicato in:Sci Rep
Autori principali: Zhang, Haifeng, Gao, Na, Tian, Xin, Liu, Tingting, Fang, Yan, Zhou, Jun, Wen, Qiang, Xu, Binbin, Qi, Bing, Gao, Jie, Li, Hongmeng, Jia, Linjing, Qiao, Hailing
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669488/
https://ncbi.nlm.nih.gov/pubmed/26635233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17671
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