Changes in cytochrome P450s-mediated drug clearance in patients with hepatocellular carcinoma in vitro and in vivo: a bottom-up approach

Hepatocellular carcinoma (HCC) accompanied by severe liver dysfunction is a serious disease, which results in altered hepatic clearance. Generally, maintenance doses depend upon drug clearance, so individual dosage regimens should be customized for HCC patients based on the condition of patients. Ba...

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Bibliografiska uppgifter
I publikationen:Oncotarget
Huvudupphovsmän: Gao, Jie, Zhou, Jun, He, Xiao-Pei, Zhang, Yun-Fei, Gao, Na, Tian, Xin, Fang, Yan, Wen, Qiang, Jia, Lin-Jing, Jin, Han, Qiao, Hai-Ling
Materialtyp: Artigo
Språk:Inglês
Publicerad: Impact Journals LLC 2016
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053749/
https://ncbi.nlm.nih.gov/pubmed/27086920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8704
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