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In Vitro and In Vivo Studies To Characterize the Clearance Mechanism and Potential Cytochrome P450 Interactions of Anidulafungin

Anidulafungin is a novel semisynthetic echinocandin with potent activity against Candida (including azole-resistant isolates) and Aspergillus spp. and is used for serious systemic fungal infections. The purpose of these studies was to characterize the clearance mechanism and potential for drug inter...

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Hlavní autoři: Damle, Bharat D., Dowell, James A., Walsky, Robert L., Weber, Gregory L., Stogniew, Martin, Inskeep, Philip B.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2650573/
https://ncbi.nlm.nih.gov/pubmed/19029327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01279-08
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