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Content and activity of human liver microsomal protein and prediction of individual hepatic clearance in vivo
The lack of information concerning individual variation in content and activity of human liver microsomal protein is one of the most important obstacles for designing personalized medicines. We demonstrated that the mean value of microsomal protein per gram of liver (MPPGL) was 39.46 mg/g in 128 hum...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4669488/ https://ncbi.nlm.nih.gov/pubmed/26635233 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17671 |
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