Content and activity of human liver microsomal protein and prediction of individual hepatic clearance in vivo

The lack of information concerning individual variation in content and activity of human liver microsomal protein is one of the most important obstacles for designing personalized medicines. We demonstrated that the mean value of microsomal protein per gram of liver (MPPGL) was 39.46 mg/g in 128 hum...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Zhang, Haifeng, Gao, Na, Tian, Xin, Liu, Tingting, Fang, Yan, Zhou, Jun, Wen, Qiang, Xu, Binbin, Qi, Bing, Gao, Jie, Li, Hongmeng, Jia, Linjing, Qiao, Hailing
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2015
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669488/
https://ncbi.nlm.nih.gov/pubmed/26635233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17671
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