Content and activity of human liver microsomal protein and prediction of individual hepatic clearance in vivo

The lack of information concerning individual variation in content and activity of human liver microsomal protein is one of the most important obstacles for designing personalized medicines. We demonstrated that the mean value of microsomal protein per gram of liver (MPPGL) was 39.46 mg/g in 128 hum...

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Publicat a:Sci Rep
Autors principals: Zhang, Haifeng, Gao, Na, Tian, Xin, Liu, Tingting, Fang, Yan, Zhou, Jun, Wen, Qiang, Xu, Binbin, Qi, Bing, Gao, Jie, Li, Hongmeng, Jia, Linjing, Qiao, Hailing
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669488/
https://ncbi.nlm.nih.gov/pubmed/26635233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17671
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