Aryl Hydrocarbon Receptor Ligand 5F 203 Induces Oxidative Stress That Triggers DNA Damage in Human Breast Cancer Cells

Breast tumors often show profound sensitivity to exogenous oxidative stress. Investigational agent 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole (5F 203) induces aryl hydrocarbon receptor (AhR)-mediated DNA damage in certain breast cancer cells. Since AhR agonists often elevate intracellular oxid...

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Bibliografski detalji
Izdano u:Chem Res Toxicol
Glavni autori: McLean, Lancelot S., Watkins, Cheri N., Campbell, Petreena, Zylstra, Dain, Rowland, Leah, Amis, Louisa H., Scott, Lia, Babb, Crystal E., Livingston, W. Joel, Darwanto, Agus, Davis, Willie L., Senthil, Maheswari, Sowers, Lawrence C., Brantley, Eileen
Format: Artigo
Jezik:Inglês
Izdano: 2015
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4662255/
https://ncbi.nlm.nih.gov/pubmed/25781201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx500485v
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