Aryl Hydrocarbon Receptor Ligand 5F 203 Induces Oxidative Stress That Triggers DNA Damage in Human Breast Cancer Cells

Breast tumors often show profound sensitivity to exogenous oxidative stress. Investigational agent 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole (5F 203) induces aryl hydrocarbon receptor (AhR)-mediated DNA damage in certain breast cancer cells. Since AhR agonists often elevate intracellular oxid...

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Xehetasun bibliografikoak
Argitaratua izan da:Chem Res Toxicol
Egile Nagusiak: McLean, Lancelot S., Watkins, Cheri N., Campbell, Petreena, Zylstra, Dain, Rowland, Leah, Amis, Louisa H., Scott, Lia, Babb, Crystal E., Livingston, W. Joel, Darwanto, Agus, Davis, Willie L., Senthil, Maheswari, Sowers, Lawrence C., Brantley, Eileen
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4662255/
https://ncbi.nlm.nih.gov/pubmed/25781201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx500485v
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