Glaucarubulone glucoside from Castela macrophylla suppresses MCF-7 breast cancer cell growth and attenuates benzo[a]pyrene-mediated CYP1A gene induction

Quassinoids often exhibit anti-oxidant and anti-proliferative activity. Emerging evidence suggests that these natural metabolites also display chemopreventive actions. In this study, we investigated the potential for the quassinoid glaucarubulone glucoside (Gg), isolated from the endemic Jamaican pl...

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Detalhes bibliográficos
Publicado no:J Appl Toxicol
Main Authors: Badal, Simone AM, Valenzuela, Malyn M. Asuncion, Zylstra, Dain, Huang, George, Vendantam, Pallavi, Francis, Sheena, Quitugua, Ashley, Amis, Louisa H., Davis, Willie, Tzeng, Tzuen-Rong J., Jacobs, Helen, Gangemi, David J., Raner, Greg, Rowland, Leah, Wooten, Jonathan, Campbell, Petreena, Brantley, Eileen, Delgoda, Rupika
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5435539/
https://ncbi.nlm.nih.gov/pubmed/28138972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jat.3436
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