Glaucarubulone glucoside from Castela macrophylla suppresses MCF-7 breast cancer cell growth and attenuates benzo[a]pyrene-mediated CYP1A gene induction

Quassinoids often exhibit anti-oxidant and anti-proliferative activity. Emerging evidence suggests that these natural metabolites also display chemopreventive actions. In this study, we investigated the potential for the quassinoid glaucarubulone glucoside (Gg), isolated from the endemic Jamaican pl...

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Published in:J Appl Toxicol
Main Authors: Badal, Simone AM, Valenzuela, Malyn M. Asuncion, Zylstra, Dain, Huang, George, Vendantam, Pallavi, Francis, Sheena, Quitugua, Ashley, Amis, Louisa H., Davis, Willie, Tzeng, Tzuen-Rong J., Jacobs, Helen, Gangemi, David J., Raner, Greg, Rowland, Leah, Wooten, Jonathan, Campbell, Petreena, Brantley, Eileen, Delgoda, Rupika
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5435539/
https://ncbi.nlm.nih.gov/pubmed/28138972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jat.3436
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