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Superoxide Dismutase 1 Protects Hepatocytes from Type I Interferon-Driven Oxidative Damage
Tissue damage caused by viral hepatitis is a major cause of morbidity and mortality worldwide. Using a mouse model of viral hepatitis, we identified virus-induced early transcriptional changes in the redox pathways in the liver, including downregulation of superoxide dismutase 1 (Sod1). Sod1(−/−) mi...
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Publicado no: | Immunity |
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Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Authors. Published by Elsevier Inc.
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4658338/ https://ncbi.nlm.nih.gov/pubmed/26588782 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2015.10.013 |
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