Characterization of CD8 T Cell-Mediated Mutations in the Immunodominant Epitope GP33-41 of Lymphocytic Choriomeningitis Virus

Cytotoxic T lymphocytes (CTLs) represent key immune effectors of the host response against chronic viruses, due to their cytotoxic response to virus-infected cells. In response to this selection pressure, viruses may accumulate escape mutations that evade CTL-mediated control. To study the emergence...

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Bibliografiska uppgifter
I publikationen:Front Immunol
Huvudupphovsmän: Smyth, Mark, Khamina, Kseniya, Popa, Alexandra, Gudipati, Venugopal, Agerer, Benedikt, Lercher, Alexander, Kosack, Lindsay, Endler, Lukas, Baazim, Hatoon, Viczenczova, Csilla, Huppa, Johannes B., Bergthaler, Andreas
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2021
Ämnen:
Immunology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8236698/
https://ncbi.nlm.nih.gov/pubmed/34194424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.638485
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