CD8(+) T cells induce cachexia during chronic viral infection

Cachexia represents a leading cause of morbidity and mortality in various cancers, chronic inflammation and infections. Understanding of the mechanisms that drive cachexia has remained limited, especially for infection-associated cachexia (IAC). Here we describe a model of reversible cachexia in mic...

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Udgivet i:Nat Immunol
Main Authors: Baazim, Hatoon, Schweiger, Martina, Moschinger, Michael, Xu, Haifeng, Scherer, Thomas, Popa, Alexandra, Gallage, Suchira, Ali, Adnan, Khamina, Kseniya, Kosack, Lindsay, Vilagos, Bojan, Smyth, Mark, Lercher, Alexander, Friske, Joachim, Merkler, Doron, Aderem, Alan, Helbich, Thomas H., Heikenwälder, Mathias, Lang, Philipp A., Zechner, Rudolf, Bergthaler, Andreas
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6531346/
https://ncbi.nlm.nih.gov/pubmed/31110314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-019-0397-y
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