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The ERBB-STAT3 Axis Drives Tasmanian Devil Facial Tumor Disease

The marsupial Tasmanian devil (Sarcophilus harrisii) faces extinction due to transmissible devil facial tumor disease (DFTD). To unveil the molecular underpinnings of this transmissible cancer, we combined pharmacological screens with an integrated systems-biology characterization. Sensitivity to in...

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Detalhes bibliográficos
Publicado no:Cancer Cell
Main Authors: Kosack, Lindsay, Wingelhofer, Bettina, Popa, Alexandra, Orlova, Anna, Agerer, Benedikt, Vilagos, Bojan, Majek, Peter, Parapatics, Katja, Lercher, Alexander, Ringler, Anna, Klughammer, Johanna, Smyth, Mark, Khamina, Kseniya, Baazim, Hatoon, de Araujo, Elvin D., Rosa, David A., Park, Jisung, Tin, Gary, Ahmar, Siawash, Gunning, Patrick T., Bock, Christoph, Siddle, Hannah V., Woods, Gregory M., Kubicek, Stefan, Murchison, Elizabeth P., Bennett, Keiryn L., Moriggl, Richard, Bergthaler, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6335503/
https://ncbi.nlm.nih.gov/pubmed/30645971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2018.11.018
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