ATDC (Ataxia Telangiectasia Group D Complementing) Promotes Radioresistance through an Interaction with the RNF8 Ubiquitin Ligase

Induction of DNA damage by ionizing radiation (IR) and/or cytotoxic chemotherapy is an essential component of cancer therapy. The ataxia telangiectasia group D complementing gene (ATDC, also called TRIM29) is highly expressed in many malignancies. It participates in the DNA damage response downstrea...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Biol Chem
Main Authors: Yang, Huibin, Palmbos, Phillip L., Wang, Lidong, Kim, Evelyn H., Ney, Gina M., Liu, Chao, Prasad, Jayendra, Misek, David E., Yu, Xiaochun, Ljungman, Mats, Simeone, Diane M.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2015
נושאים:
Signal Transduction
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646387/
https://ncbi.nlm.nih.gov/pubmed/26381412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.665489
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