ATDC (Ataxia Telangiectasia Group D Complementing) Promotes Radioresistance through an Interaction with the RNF8 Ubiquitin Ligase

Induction of DNA damage by ionizing radiation (IR) and/or cytotoxic chemotherapy is an essential component of cancer therapy. The ataxia telangiectasia group D complementing gene (ATDC, also called TRIM29) is highly expressed in many malignancies. It participates in the DNA damage response downstrea...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Yang, Huibin, Palmbos, Phillip L., Wang, Lidong, Kim, Evelyn H., Ney, Gina M., Liu, Chao, Prasad, Jayendra, Misek, David E., Yu, Xiaochun, Ljungman, Mats, Simeone, Diane M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646387/
https://ncbi.nlm.nih.gov/pubmed/26381412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.665489
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