ATDC/TRIM29 drives invasive bladder cancer formation through microRNA-mediated and epigenetic mechanisms

Bladder cancer is a common and deadly malignancy but its treatment has advanced little due to poor understanding of the factors and pathways that promote disease. ATDC/TRIM29 is a highly expressed gene in several lethal tumor types, including bladder tumors, but its role as a pathogenic driver has n...

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Udgivet i:Cancer Res
Main Authors: Palmbos, Phillip L., Wang, Lidong, Yang, Huibin, Wang, Yin, Leflein, Jacob, Ahmet, McKenzie L., Wilkinson, John E., Kumar-Sinha, Chandan, Ney, Gina M., Tomlins, Scott A., Daignault, Stephanie, Kunju, Lakshmi. P., Wu, Xue-Ru, Lotan, Yair, Liebert, Monica, Ljungman, Mats E., Simeone, Diane M.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4668224/
https://ncbi.nlm.nih.gov/pubmed/26471361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-0603
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