טוען...
ATDC is required for the initiation of KRAS-induced pancreatic tumorigenesis
Pancreatic adenocarcinoma (PDA) is an aggressive disease driven by oncogenic KRAS and characterized by late diagnosis and therapeutic resistance. Here we show that deletion of the ataxia-telangiectasia group D-complementing (Atdc) gene, whose human homolog is up-regulated in the majority of pancreat...
שמור ב:
| הוצא לאור ב: | Genes Dev |
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| Main Authors: | , , , , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Cold Spring Harbor Laboratory Press
2019
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6546061/ https://ncbi.nlm.nih.gov/pubmed/31048544 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.323303.118 |
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