ATDC induces an invasive switch in KRAS-induced pancreatic tumorigenesis

The initiation of pancreatic ductal adenocarcinoma (PDA) is linked to activating mutations in KRAS. However, in PDA mouse models, expression of oncogenic mutant KRAS during development gives rise to tumors only after a prolonged latency or following induction of pancreatitis. Here we describe a nove...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Wang, Lidong, Yang, Huibin, Abel, Ethan V., Ney, Gina M., Palmbos, Phillip L., Bednar, Filip, Zhang, Yaqing, Leflein, Jacob, Waghray, Meghna, Owens, Scott, Wilkinson, John E., Prasad, Jayendra, Ljungman, Mats, Rhim, Andrew D., Pasca di Magliano, Marina, Simeone, Diane M.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4298136/
https://ncbi.nlm.nih.gov/pubmed/25593307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.253591.114
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados