ATDC/TRIM29 phosphorylation by ATM/MAPKAP kinase 2 mediates radioresistance in pancreatic cancer cells

Pancreatic ductal adenocarcinoma (PDAC) is characterized by therapeutic resistance for which the basis is poorly understood. Here we report that the DNA and p53 binding protein ATDC/TRIM29, which is highly expressed in PDAC, plays a critical role in DNA damage signaling and radioresistance in pancre...

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Библиографические подробности
Главные авторы: Wang, Lidong, Yang, Huibin, Palmbos, Phillip L., Ney, Gina, Detzler, Taylor Ann, Coleman, Dawn, Leflein, Jacob, Davis, Mary, Zhang, Min, Tang, Wenhua, Hicks, J. Kevin, Helchowski, Corey M., Prasad, Jayendra, Lawrence, Theodore S., Xu, Liang, Yu, Xiaochun, Canman, Christine E., Ljungman, Mats, Simeone, Diane M.
Формат: Artigo
Язык:Inglês
Опубликовано: 2014
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3961828/
https://ncbi.nlm.nih.gov/pubmed/24469230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-2289
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