Homozygous deficiency of ubiquitin-ligase ring-finger protein RNF168 mimics the radiosensitivity syndrome of ataxia-telangiectasia

Maintaining genomic integrity is critical to avoid life-threatening disorders, such as premature aging, neurodegeneration and cancer. A multiprotein cascade operates at sites of DNA double-strand breaks (DSBs) to recognize, signal and repair damage. RNF168 (ring-finger nuclear factor) contributes to...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Devgan, S S, Sanal, O, Doil, C, Nakamura, K, Nahas, S A, Pettijohn, K, Bartek, J, Lukas, C, Lukas, J, Gatti, R A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3178430/
https://ncbi.nlm.nih.gov/pubmed/21394101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2011.18
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados