Structural characterization of human cholesterol 7α-hydroxylase

Hepatic conversion to bile acids is a major elimination route for cholesterol in mammals. CYP7A1 catalyzes the first and rate-limiting step in classic bile acid biosynthesis, converting cholesterol to 7α-hydroxycholesterol. To identify the structural determinants that govern the stereospecific hydro...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Lipid Res
Hlavní autoři: Tempel, Wolfram, Grabovec, Irina, MacKenzie, Farrell, Dichenko, Yaroslav V., Usanov, Sergey A., Gilep, Andrei A., Park, Hee-Won, Strushkevich, Natallia
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Biochemistry and Molecular Biology 2014
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4617357/
https://ncbi.nlm.nih.gov/pubmed/24927729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M050765
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky