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Structural characterization of human cholesterol 7α-hydroxylase
Hepatic conversion to bile acids is a major elimination route for cholesterol in mammals. CYP7A1 catalyzes the first and rate-limiting step in classic bile acid biosynthesis, converting cholesterol to 7α-hydroxycholesterol. To identify the structural determinants that govern the stereospecific hydro...
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| 出版年: | J Lipid Res |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The American Society for Biochemistry and Molecular Biology
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4617357/ https://ncbi.nlm.nih.gov/pubmed/24927729 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M050765 |
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