Human Lanosterol 14-Alpha Demethylase (CYP51A1) Is a Putative Target for Natural Flavonoid Luteolin 7,3′-Disulfate

Widespread pathologies such as atherosclerosis, metabolic syndrome and cancer are associated with dysregulation of sterol biosynthesis and metabolism. Cholesterol modulates the signaling pathways of neoplastic transformation and tumor progression. Lanosterol 14-alpha demethylase (cytochrome P450(51)...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Molecules
Prif Awduron: Kaluzhskiy, Leonid, Ershov, Pavel, Yablokov, Evgeniy, Shkel, Tatsiana, Grabovec, Irina, Mezentsev, Yuri, Gnedenko, Oksana, Usanov, Sergey, Shabunya, Polina, Fatykhava, Sviatlana, Popov, Alexander, Artyukov, Aleksandr, Styshova, Olga, Gilep, Andrei, Strushkevich, Natallia, Ivanov, Alexis
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2021
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8070018/
https://ncbi.nlm.nih.gov/pubmed/33924405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26082237
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