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Structural characterization of human cholesterol 7α-hydroxylase
Hepatic conversion to bile acids is a major elimination route for cholesterol in mammals. CYP7A1 catalyzes the first and rate-limiting step in classic bile acid biosynthesis, converting cholesterol to 7α-hydroxycholesterol. To identify the structural determinants that govern the stereospecific hydro...
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| Publicado no: | J Lipid Res |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Biochemistry and Molecular Biology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4617357/ https://ncbi.nlm.nih.gov/pubmed/24927729 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M050765 |
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