Ablation of HRC alleviates cardiac arrhythmia and improves abnormal Ca handling in CASQ2 knockout mice prone to CPVT

AIMS: Cardiac calsequestrin (CASQ2) and histidine-rich Ca-binding protein (HRC) are sarcoplasmic reticulum (SR) Ca-binding proteins that regulate SR Ca release in mammalian heart. Deletion of either CASQ2 or HRC results in relatively mild phenotypes characterized by preserved cardiac structure and f...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cardiovasc Res
Main Authors: Liu, Bin, Ho, Hsiang-Ting, Brunello, Lucia, Unudurthi, Sathya D., Lou, Qing, Belevych, Andriy E., Qian, Lan, Kim, Do Han, Cho, Chunghee, Janssen, Paul M. L., Hund, Thomas J., Knollmann, Bjorn C., Kranias, Evangelia G., Györke, Sándor
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
ORIGINAL ARTICLES
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4614688/
https://ncbi.nlm.nih.gov/pubmed/26410369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvv222
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados