Alternating membrane potential/calcium interplay underlies repetitive focal activity in a genetic model of calcium-dependent atrial arrhythmias

Aberrant diastolic calcium (Ca) release due to leaky ryanodine receptors (RyR2s) has been recently associated with atrial fibrillation (AF) and catecholaminergic polymorphic ventricular tachycardia (CPVT). However, it remains unclear how diastolic Ca release contributes to the rising of rapid repeti...

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Detaylı Bibliyografya
Yayımlandı:J Physiol
Asıl Yazarlar: Lou, Qing, Belevych, Andriy E, Radwański, Przemysław B, Liu, Bin, Kalyanasundaram, Anuradha, Knollmann, Bjorn C, Fedorov, Vadim V, Györke, Sándor
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BlackWell Publishing Ltd 2015
Konular:
Research Papers
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4376423/
https://ncbi.nlm.nih.gov/pubmed/25384790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2014.280784
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