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Store-dependent deactivation: Cooling the chain-reaction of myocardial calcium signaling

In heart cells, Ca(2+) released from the internal storage unit, the sarcoplasmic reticulum (SR) through ryanodine receptor (RyR2) channels is the predominant determinant of cardiac contractility. Evidence obtained in recent years suggests that SR Ca(2+) release is tightly regulated not only by cytos...

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Detalhes bibliográficos
Main Authors: Radwański, Przemysław B., Belevych, Andriy E., Brunello, Lucia, Carnes, Cynthia A., Györke, Sándor
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068615/
https://ncbi.nlm.nih.gov/pubmed/23108187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2012.10.008
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