Store-dependent deactivation: Cooling the chain-reaction of myocardial calcium signaling

In heart cells, Ca(2+) released from the internal storage unit, the sarcoplasmic reticulum (SR) through ryanodine receptor (RyR2) channels is the predominant determinant of cardiac contractility. Evidence obtained in recent years suggests that SR Ca(2+) release is tightly regulated not only by cytos...

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Bibliografiske detaljer
Main Authors: Radwański, Przemysław B., Belevych, Andriy E., Brunello, Lucia, Carnes, Cynthia A., Györke, Sándor
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068615/
https://ncbi.nlm.nih.gov/pubmed/23108187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2012.10.008
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