Highly Selective Salicylketoxime-Based Estrogen Receptor β Agonists Display Antiproliferative Activities in a Glioma Model

[Image: see text] Estrogen receptor β (ERβ) selective agonists are considered potential therapeutic agents for a variety of pathological conditions, including several types of cancer. Their development is particularly challenging, since differences in the ligand binding cavities of the two ER subtyp...

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Pubblicato in:J Med Chem
Autori principali: Paterni, Ilaria, Bertini, Simone, Granchi, Carlotta, Tuccinardi, Tiziano, Macchia, Marco, Martinelli, Adriano, Caligiuri, Isabella, Toffoli, Giuseppe, Rizzolio, Flavio, Carlson, Kathryn E., Katzenellenbogen, Benita S., Katzenellenbogen, John A., Minutolo, Filippo
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2015
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4610302/
https://ncbi.nlm.nih.gov/pubmed/25559213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm501829f
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