Učitavanje...
RlmCD-mediated U747 methylation promotes efficient G748 methylation by methyltransferase RlmA(II) in 23S rRNA in Streptococcus pneumoniae; interplay between two rRNA methylations responsible for telithromycin susceptibility
Adenine at position 752 in a loop of helix 35 from positions 745 to 752 in domain II of 23S rRNA is involved in binding to the ribosome of telithromycin (TEL), a member of ketolides. Methylation of guanine at position 748 by the intrinsic methyltransferase RlmA(II) enhances binding of telithromycin...
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| Izdano u: | Nucleic Acids Res |
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| Glavni autori: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2015
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4605293/ https://ncbi.nlm.nih.gov/pubmed/26365244 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv609 |
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