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Methylation of 23S rRNA nucleotide G745 is a secondary function of the RlmA(I) methyltransferase

Several groups of Gram-negative bacteria possess an RlmA(I) methyltransferase that methylates 23S rRNA nucleotide G745 at the N1 position. Inactivation of rlmA(I) in Acinetobacter calcoaceticus and Escherichia coli reduces growth rates by at least 30%, supposedly due to ribosome malfunction. Wild-ty...

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Detalhes bibliográficos
Main Authors: LIU, MINGFU, NOVOTNY, GUY W., DOUTHWAITE, STEPHEN
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2004 by RNA Society 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370659/
https://ncbi.nlm.nih.gov/pubmed/15388872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.7820104
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