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Methylation of 23S rRNA nucleotide G745 is a secondary function of the RlmA(I) methyltransferase

Several groups of Gram-negative bacteria possess an RlmA(I) methyltransferase that methylates 23S rRNA nucleotide G745 at the N1 position. Inactivation of rlmA(I) in Acinetobacter calcoaceticus and Escherichia coli reduces growth rates by at least 30%, supposedly due to ribosome malfunction. Wild-ty...

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Auteurs principaux: LIU, MINGFU, NOVOTNY, GUY W., DOUTHWAITE, STEPHEN
Format: Artigo
Langue:Inglês
Publié: Copyright 2004 by RNA Society 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370659/
https://ncbi.nlm.nih.gov/pubmed/15388872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.7820104
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