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Methylation of 23S rRNA nucleotide G745 is a secondary function of the RlmA(I) methyltransferase

Several groups of Gram-negative bacteria possess an RlmA(I) methyltransferase that methylates 23S rRNA nucleotide G745 at the N1 position. Inactivation of rlmA(I) in Acinetobacter calcoaceticus and Escherichia coli reduces growth rates by at least 30%, supposedly due to ribosome malfunction. Wild-ty...

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Bibliografiske detaljer
Main Authors: LIU, MINGFU, NOVOTNY, GUY W., DOUTHWAITE, STEPHEN
Format: Artigo
Sprog:Inglês
Udgivet: Copyright 2004 by RNA Society 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370659/
https://ncbi.nlm.nih.gov/pubmed/15388872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.7820104
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