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Structure of 23S rRNA hairpin 35 and its interaction with the tylosin-resistance methyltransferase RlmA(II)

The bacterial rRNA methyltransferase RlmA(II) (formerly TlrB) contributes to resistance against tylosin-like 16-membered ring macrolide antibiotics. RlmA(II) was originally discovered in the tylosin-producer Streptomyces fradiae, and members of this subclass of methyltransferases have subsequently b...

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Detalhes bibliográficos
Main Authors: Lebars, Isabelle, Yoshizawa, Satoko, Stenholm, Anne R., Guittet, Eric, Douthwaite, Stephen, Fourmy, Dominique
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC140097/
https://ncbi.nlm.nih.gov/pubmed/12514124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg022
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