A single methyltransferase YefA (RlmCD) catalyses both m(5)U747 and m(5)U1939 modifications in Bacillus subtilis 23S rRNA

Methyltransferases that use S-adenosylmethionine (AdoMet) as a cofactor to catalyse 5-methyl uridine (m(5)U) formation in tRNAs and rRNAs are widespread in Bacteria and Eukaryota, and are also found in certain Archaea. These enzymes belong to the COG2265 cluster, and the Gram-negative bacterium Esch...

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Bibliographic Details
Main Authors: Desmolaize, Benoit, Fabret, Céline, Brégeon, Damien, Rose, Simon, Grosjean, Henri, Douthwaite, Stephen
Format: Artigo
Language:Inglês
Published: Oxford University Press 2011
Subjects:
RNA
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3241648/
https://ncbi.nlm.nih.gov/pubmed/21824914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr626
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