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Identifying the methyltransferases for m(5)U747 and m(5)U1939 in 23S rRNA using MALDI mass spectrometry

There are three sites of m(5)U modification in Escherichia coli stable RNAs: one at the invariant tRNA position U54 and two in 23S rRNA at the phylogenetically conserved positions U747 and U1939. Each of these sites is modified by its own methyltransferase, and the tRNA methyltransferase, TrmA, is w...

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Detalhes bibliográficos
Main Authors: Madsen, Christian Toft, Mengel-Jørgensen, Jonas, Kirpekar, Finn, Douthwaite, Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC169892/
https://ncbi.nlm.nih.gov/pubmed/12907714
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