Identifying the methyltransferases for m(5)U747 and m(5)U1939 in 23S rRNA using MALDI mass spectrometry

There are three sites of m(5)U modification in Escherichia coli stable RNAs: one at the invariant tRNA position U54 and two in 23S rRNA at the phylogenetically conserved positions U747 and U1939. Each of these sites is modified by its own methyltransferase, and the tRNA methyltransferase, TrmA, is w...

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Main Authors: Madsen, Christian Toft, Mengel-Jørgensen, Jonas, Kirpekar, Finn, Douthwaite, Stephen
格式: Artigo
語言:Inglês
出版: Oxford University Press 2003
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC169892/
https://ncbi.nlm.nih.gov/pubmed/12907714
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