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Mapping posttranscriptional modifications in 5S ribosomal RNA by MALDI mass spectrometry.

We present a method to screen RNA for posttranscriptional modifications based on Matrix Assisted Laser Desorption/Ionization mass spectrometry (MALDI-MS). After the RNA is digested to completion with a nucleotide-specific RNase, the fragments are analyzed by mass spectrometry. A comparison of the ob...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Kirpekar, F, Douthwaite, S, Roepstorff, P
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2000
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1369914/
https://ncbi.nlm.nih.gov/pubmed/10688367
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