Unveiling the structural features that determine the dual methyltransferase activities of Streptococcus pneumoniae RlmCD

Methyltransferase RlmCD was previously shown to be responsible for the introduction of C5 methylation at both U747 and U1939 of the 23S ribosomal RNA in Streptococcus pneumoniae. Intriguingly, its structural homologue, RumA, can only catalyze the methylation of U1939, while RlmC is the dedicated enz...

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Bibliografiset tiedot
Julkaisussa:PLoS Pathog
Päätekijät: Jiang, Yiyang, Yu, Hailong, Li, Fudong, Cheng, Lin, Zhu, Lingru, Shi, Yunyu, Gong, Qingguo
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2018
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6235398/
https://ncbi.nlm.nih.gov/pubmed/30388185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007379
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