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Probing the Structural Requirements of Non-electrophilic Naphthalene-Based Nrf2 Activators
Activation of the transcription factor Nrf2 has been posited to be a promising therapeutic strategy in a number of inflammatory and oxidative stress diseases due to its regulation of detoxifying enzymes. In this work, we have developed a comprehensive structure-activity relationship around a known,...
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| Publicado en: | Eur J Med Chem |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4600463/ https://ncbi.nlm.nih.gov/pubmed/26363505 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2015.08.049 |
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