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Conditional Deletion of Nrf2 in Airway Epithelium Exacerbates Acute Lung Injury and Impairs the Resolution of Inflammation

Oxidant stress, resulting from an excess of reactive electrophiles produced in the lung by both resident (epithelial and endothelial) and infiltrated leukocytes, is thought to play an obligatory role in tissue injury and abnormal repair. Previously, using a conventional (whole-body) knockout model,...

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Detalhes bibliográficos
Main Authors: Reddy, Narsa M., Potteti, Haranatha R., Mariani, Thomas J., Biswal, Shyam, Reddy, Sekhar P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262666/
https://ncbi.nlm.nih.gov/pubmed/21659655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2011-0144OC
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