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DISRUPTION OF NRF2 IMPAIRS THE RESOLUTION OF HYPEROXIA-INDUCED ACUTE LUNG INJURY AND INFLAMMATION IN MICE

Aberrant tissue repair and persistent inflammation following oxidant-mediated acute lung injury (ALI) can lead to the development and progression of various pulmonary diseases, but the mechanisms underlying these processes remain unclear. Hyperoxia is widely used in the treatment of pulmonary diseas...

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Main Authors: Reddy, Narsa M, Kleeberger, Steven R, Kensler, Thomas W., Yamamoto, Masayuki, Hassoun, Paul M, Reddy, Sekhar P
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820248/
https://ncbi.nlm.nih.gov/pubmed/19454723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0804248
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