Probing the Structural Requirements of Non-electrophilic Naphthalene-Based Nrf2 Activators

Activation of the transcription factor Nrf2 has been posited to be a promising therapeutic strategy in a number of inflammatory and oxidative stress diseases due to its regulation of detoxifying enzymes. In this work, we have developed a comprehensive structure-activity relationship around a known,...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Eur J Med Chem
Main Authors: Jain, Atul D., Potteti, Haranatha, Richardson, Benjamin G., Kingsley, Laura, Luciano, Julia P., Ryuzoji, Aya F., Lee, Hyun, Krunic, Aleksej, Mesecar, Andrew D., Reddy, Sekhar P., Moore, Terry W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600463/
https://ncbi.nlm.nih.gov/pubmed/26363505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2015.08.049
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados