Probing the Structural Requirements of Non-electrophilic Naphthalene-Based Nrf2 Activators

Activation of the transcription factor Nrf2 has been posited to be a promising therapeutic strategy in a number of inflammatory and oxidative stress diseases due to its regulation of detoxifying enzymes. In this work, we have developed a comprehensive structure-activity relationship around a known,...

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Bibliografski detalji
Izdano u:Eur J Med Chem
Glavni autori: Jain, Atul D., Potteti, Haranatha, Richardson, Benjamin G., Kingsley, Laura, Luciano, Julia P., Ryuzoji, Aya F., Lee, Hyun, Krunic, Aleksej, Mesecar, Andrew D., Reddy, Sekhar P., Moore, Terry W.
Format: Artigo
Jezik:Inglês
Izdano: 2015
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600463/
https://ncbi.nlm.nih.gov/pubmed/26363505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2015.08.049
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