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Preclinical Pharmacokinetic Considerations for the Development of Antibody Drug Conjugates

Antibody drug conjugates (ADCs) are an emerging new class of targeted therapeutics for cancer that use antibodies to deliver cytotoxic drugs to cancer cells. There are two FDA approved ADCs on the market and over 30 ADCs in the clinical pipeline against a number of different cancer types. The struct...

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Detalhes bibliográficos
Publicado no:Pharm Res
Main Authors: Kamath, Amrita V., Iyer, Suhasini
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4596897/
https://ncbi.nlm.nih.gov/pubmed/25446773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-014-1584-z
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