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Using the Lessons Learned From the Clinic to Improve the Preclinical Development of Antibody Drug Conjugates

The treatment options for cancer patients include surgery, chemotherapeutics, radiation therapy, antibody therapy and various combinations of these therapies. The challenge with each therapy is finding the balance between maximizing the anti-tumor efficacy while minimizing the dose limiting toxiciti...

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Publicat a:Pharm Res
Autors principals: Jackson, Dowdy, Stover, David
Format: Artigo
Idioma:Inglês
Publicat: Springer US 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4596896/
https://ncbi.nlm.nih.gov/pubmed/25339341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-014-1536-7
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