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Preclinical Pharmacokinetic Considerations for the Development of Antibody Drug Conjugates

Antibody drug conjugates (ADCs) are an emerging new class of targeted therapeutics for cancer that use antibodies to deliver cytotoxic drugs to cancer cells. There are two FDA approved ADCs on the market and over 30 ADCs in the clinical pipeline against a number of different cancer types. The struct...

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Publicat a:Pharm Res
Autors principals: Kamath, Amrita V., Iyer, Suhasini
Format: Artigo
Idioma:Inglês
Publicat: Springer US 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4596897/
https://ncbi.nlm.nih.gov/pubmed/25446773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-014-1584-z
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