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Preclinical Pharmacokinetic Considerations for the Development of Antibody Drug Conjugates

Antibody drug conjugates (ADCs) are an emerging new class of targeted therapeutics for cancer that use antibodies to deliver cytotoxic drugs to cancer cells. There are two FDA approved ADCs on the market and over 30 ADCs in the clinical pipeline against a number of different cancer types. The struct...

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Detalles Bibliográficos
Publicado en:Pharm Res
Autores principales: Kamath, Amrita V., Iyer, Suhasini
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer US 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4596897/
https://ncbi.nlm.nih.gov/pubmed/25446773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-014-1584-z
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