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Challenges and advances in the assessment of the disposition of antibody‐drug conjugates
Antibody‐drug conjugates (ADCs) are a rapidly growing therapeutic platform for the treatment of cancer. ADCs consist of a cytotoxic small molecule drug linked to an antibody to provide targeted delivery of the cytotoxic agent to the tumor. Understanding the pharmacokinetics (PK) and pharmacodynamics...
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| Publicado no: | Biopharm Drug Dispos |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5032988/ https://ncbi.nlm.nih.gov/pubmed/25904406 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bdd.1957 |
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